Today's crossword puzzle clue is a general knowledge one: Second-longest river in Italy after the Po, flowing southeast from the Alps to the Adriatic. We will try to find the right answer to this particular crossword clue. Here are the possible solutions for "Second-longest river in Italy after the Po, flowing southeast from the Alps to the Adriatic" clue. It was last seen in British general knowledge crossword. We have 1 possible answer in our database.