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Today's crossword puzzle clue is a general knowledge one: Ancient region of central Italy, also a suburb of Stoke-on-Trent. We will try to find the right answer to this particular crossword clue. Here are the possible solutions for "Ancient region of central Italy, also a suburb of Stoke-on-Trent" clue. It was last seen in British general knowledge crossword. We have 1 possible answer in our database.